Publications

Shirole NH, Kesar D, Lee Y, Goodale A, Syamala S, Kukreja S, Li R, Qiu X, Yu W, Goldman S, Cejas P, Long HW, Adelman K, Doench JG, Sellers WR, Kaelin WG Jr. Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer.

Narducci DN, Hansen AS. Putative looping factor ZNF143/ZFP143 is an essential transcriptional regulator with no looping function.

Jiang Q, Braun DA, Clauser KR, Ramesh V, Shirole NH, Duke-Cohan JE, Nabilsi N, Kramer NJ, Forman C, Lippincott IE, Klaeger S, Phulphagar KM, Chea V, Kim N, Vanasse AP, Saad E, Parsons T, Carr-Reynolds M, Carulli I, Pinjusic K, Jiang Y, Li R, Syamala S, Rachimi S, Verzani EK, Stevens JD, Lane WJ, Camp SY, Meli K, Pappalardi MB, Herbert ZT, Qiu X, Cejas P, Long HW, Shukla SA, Van Allen EM, Choueiri TK, Churchman S, Abelin JG, Gurer C, MacBeath G, Childs RW, Carr SA, Keskin DB, Wu CJ, Kaelin WG. HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.

Baluapuri A, Zhao NC, Marina RJ, Huang KL, Kuzkina A, Amodeo ME, Stein CB, Ahn LY, Farr JS, Schaffer AE, Khurana V, Wagner EJ, Adelman K. Integrator loss leads to dsRNA formation that triggers the integrated stress response.

Kim G, Carroll CL, Wakefield ZP, Tuncay M, Fiszbein A. U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation.

Wang Y, Baluapuri A, Manokaran C, Ni J, Jiang T, Janssens RC, Marteijn JA, Adelman K, Zhao J, Roberts TM. Dual Modes of Gene Regulation by CDK12.

Zhang S, Engel K, Fahs A, Malone CF, Ross K, Just M, Guedes B, Granum D, Oristian KM, Kovach A, Alexe G, Digiovanni G, Barbar L, Bentley R, Cerda-Smith C, Le Roux O, Mendes E, Zimmerman SP, Rees M, Roth J, Shern JF, Wood KC, Counter CM, Linardic CM, Stegmaier K. CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-driven Alveolar Rhabdomyosarcoma.

Pulice JL, Meyerson M. Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma.

Martin-Rufino JD, Caulier A, Lee S, Castano N, King E, Joubran S, Jones M, Goldman SR, Arora UP, Wahlster L, Lander ES, Sankaran VG. Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes.

Kaye EG, Basavaraju K, Nelson GM, Zomer HD, Roy D, Joseph II, Rajabi-Toustani R, Qiao H, Adelman K, Reddi PP. RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis.

Mehta S, Buyanbat A, Kai Y, Orkin SH. Mechanistic and kinetic insights into transcription factor biology via acute protein depletion.

Heikamp EB, Martucci C, Henrich JA, Neel DS, Mahendra-Rajah S, Rice H, Wenge DV, Perner F, Wen Y, Hatton C, Armstrong SA. NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AML.